{"entity":{"id":"nct05673148","kind":"trial","name":"Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Alliance for Clinical Trials in Oncology, now recruiting.","summary":"Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial is a phase 2, randomised interventional study registered as NCT05673148 by Alliance for Clinical Trials in Oncology, with a registry enrolment figure of 146 participants, started 2023-10-09 and due to reach its primary completion in 2028-07-03. Interventions recorded: Stereotactic Ablative Radiotherapy; Resection; Microwave Ablation; Chemotherapy; Computed Tomography; Magnetic Resonance Imaging; Positron Emission Tomography. Conditions listed: Metastatic Colorectal Adenocarcinoma; Stage IV Colorectal Cancer AJCC v8; Oligometastatic Colorectal Carcinoma. Primary outcome: Overall Survival (OS). Colorectal eligibility wording from the registry: \"* PRE-REGISTRATION (STEP 0): Pathologically proven diagnosis of metastatic colorectal adenocarcinoma with metastases (biopsy from primary tumor or metastatic site is acceptable)\". Sites: Canada, United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05673148","url":"https://clinicaltrials.gov/study/NCT05673148"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["sbrt","thermal-ablation"],"targets":[],"drugs":[],"companies":["alliance-oncology"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05673148","phase":"2","setting":"A Pragmatic Randomized Phase II Trial Evaluating Total Ablative Therapy for Patients With Limited Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery (ERASur)","sponsor":"Alliance for Clinical Trials in Oncology","enrolled":146,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05673148/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"},{"id":"thermal-ablation","kind":"technology","name":"Thermal ablation (RFA, microwave, cryo)","route":"/technologies/thermal-ablation/"}],"company":[{"id":"alliance-oncology","kind":"company","name":"Alliance for Clinical Trials in Oncology","route":"/companies/alliance-oncology/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}