{"entity":{"id":"nct05676931","kind":"trial","name":"Study With Various Immunotherapy Treatments in Participants With Lung Cancer","aka":[],"tldr":"A phase 2 trial of Domvanalimab, Quemliclustat, Zimberelimab in non-small-cell lung cancer and small-cell lung cancer, run by Gilead Sciences, active and no longer recruiting.","summary":"Study With Various Immunotherapy Treatments in Participants With Lung Cancer is a phase 2 interventional study registered as NCT05676931 by Gilead Sciences, with 400 participants planned, started 2023-02-21 and due to reach its primary completion in 2027-12. Interventions recorded: Domvanalimab, Quemliclustat, Zimberelimab, Docetaxel, Platinum-Based Doublet. Conditions listed: Advanced Non-Small Cell Lung Cancer. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT05676931","url":"https://clinicaltrials.gov/study/NCT05676931"}],"tags":["ctgov-ingest"],"related":[],"cancers":["nsclc","sclc"],"sections":[],"technologies":[],"targets":[],"drugs":["domvanalimab","quemliclustat","zimberelimab","docetaxel"],"companies":["gilead"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT05676931","phase":"2","setting":"A Phase II, Open-label, Platform Study, to Evaluate Immunotherapy-based Combinations in Participants With Advanced Non-Small Cell Lung Cancer","sponsor":"Gilead Sciences","enrolled":400,"outcomes":[]},"route":"/trials/nct05676931/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"docetaxel","kind":"drug","name":"Docetaxel","route":"/drugs/docetaxel/"},{"id":"domvanalimab","kind":"drug","name":"Domvanalimab","route":"/drugs/domvanalimab/"},{"id":"quemliclustat","kind":"drug","name":"Quemliclustat","route":"/drugs/quemliclustat/"},{"id":"zimberelimab","kind":"drug","name":"Zimberelimab","route":"/drugs/zimberelimab/"}],"company":[{"id":"gilead","kind":"company","name":"Gilead Sciences (incl. Kite)","route":"/companies/gilead/"}]}}