{"entity":{"id":"nct05692999","kind":"trial","name":"Maintenance Pembrolizumab at Usual or Low doSE in Non-squamous Lung Cancer: a Non-inferiority Study","aka":["Pulse"],"tldr":"A phase 3 trial in lung cancer, run by Gustave Roussy, Cancer Campus, Grand Paris, now recruiting.","summary":"Maintenance Pembrolizumab at Usual or Low doSE in Non-squamous Lung Cancer: a Non-inferiority Study is a phase 3, randomised interventional study registered as NCT05692999 by Gustave Roussy, Cancer Campus, Grand Paris, with a registry enrolment figure of 1166 participants, started 2023-03-20 and due to reach its primary completion in 2029-01. Interventions recorded: Pembrolizumab 200 mg Q6W; Pemetrexed 500 mg/m^2 Q3W; Pembrolizumab 200 mg Q3W or 400 mg Q6W. Conditions listed: Metastatic Non-squamous Lung Cancer. Primary outcome: Overall survival. Lung eligibility wording from the registry: \"Histologically or cytologically confirmed diagnosis of non-squamous non-small cell lung cancer (NSCLC)\". Sites: Belgium, France, Spain. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT05692999","url":"https://clinicaltrials.gov/study/NCT05692999"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["lung-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05692999","phase":"3","setting":"Maintenance Pembrolizumab at Usual or Low doSE in Non-squamous Lung Cancer: a Non-inferiority Study","sponsor":"Gustave Roussy, Cancer Campus, Grand Paris","enrolled":1166,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05692999/","neighbours":{"cancer":[{"id":"lung-cancer","kind":"cancer","name":"Lung cancer (all types)","route":"/cancers/lung-cancer/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}