{"entity":{"id":"nct05742425","kind":"trial","name":"Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Second Affiliated Hospital, Zhejiang University, School of Medicine, now recruiting.","summary":"Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of Colon Cancer Peritoneal Metastases is a phase 2, interventional study registered as NCT05742425 by Second Affiliated Hospital, Zhejiang University, School of Medicine, with a registry enrolment figure of 30 participants, started 2023-03 and due to reach its primary completion in 2028-03. Interventions recorded: Serplulimab Combined With FOLFIRI and Bevacizumab. Conditions listed: Unresectable Colon Cancer Peritoneal Metastases; PMMR/Ras/BRAF Wild-type. Primary outcome: Disease-free survival (DFS). Colorectal eligibility wording from the registry: \"Colon cancer was confirmed by histology, and its gene detection was pMMR/MSS and RAS/BRAF wild-type\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05742425","url":"https://clinicaltrials.gov/study/NCT05742425"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05742425","phase":"2","setting":"The Efficacy and Safety of Serplulimab Combined With FOLFIRI and Bevacizumab in the Treatment of pMMR/Ras/BRAF Wild-type Unresectable Colon Cancer Peritoneal Metastases: a Multicenter Single-arm Phase II Trial","sponsor":"Second Affiliated Hospital, Zhejiang University, School of Medicine","enrolled":30,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05742425/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}