{"entity":{"id":"nct05747716","kind":"trial","name":"SBRT Combined With Fruquintinib Plus PD-1/CTLA-4 Antibody for Third-line Treatment in mCRC","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, not yet recruiting.","summary":"SBRT Combined With Fruquintinib Plus PD-1/CTLA-4 Antibody for Third-line Treatment in mCRC is a phase 2, interventional study registered as NCT05747716 by Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, with a registry enrolment figure of 44 participants, started 2023-02-28 and due to reach its primary completion in 2026-12-31. Interventions recorded: SBRT, Fruquintinib, Cadonilimab. Conditions listed: Metastatic Colorectal Cancer. Primary outcome: Progression free survival. Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05747716","url":"https://clinicaltrials.gov/study/NCT05747716"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["sbrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05747716","phase":"2","setting":"SBRT Combined With Fruquintinib Plus PD-1/CTLA-4 Antibody Cadonilimab for Third-line Treatment in Metastatic Colonrectal Cancer.","sponsor":"Union Hospital, Tongji Medical College, Huazhong University of Science and Technology","enrolled":44,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05747716/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}