{"entity":{"id":"nct05748145","kind":"trial","name":"Metronidazole as Preoperative Therapy in CRC / FusoMetro-001","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Oncology Institute of Southern Switzerland, now recruiting.","summary":"Metronidazole as Preoperative Therapy in CRC / FusoMetro-001 is a phase 2, interventional study registered as NCT05748145 by Oncology Institute of Southern Switzerland, with a registry enrolment figure of 40 participants, started 2023-09-11 and due to reach its primary completion in 2026-12-31. Interventions recorded: Metronidazole Oral. Conditions listed: Colorectal Cancer. Primary outcome: Impact of metronidazole on F.n. loads in CRC tissues.. Colorectal eligibility wording from the registry: \"* Untreated, primary colorectal adenocarcinoma (\\> 15 cm from the anal verge)\". Sites: Switzerland. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05748145","url":"https://clinicaltrials.gov/study/NCT05748145"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05748145","phase":"2","setting":"Preoperative Treatment With Metronidazole to Evaluate the Efficacy in Reducing Fusobacterium Nucleatum Tumor Colonization in Patients With Colorectal Cancer (CRC): a Proof-of-concept Trial","sponsor":"Oncology Institute of Southern Switzerland","enrolled":40,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05748145/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}