{"entity":{"id":"nct05764928","kind":"trial","name":"Evaluate the Safety and Efficacy of BLEX 404 Oral Liquid Combined With Pemetrexed + Cisplatin Therapy","aka":[],"tldr":"A phase 1/2 trial in lung cancer, run by Rgene Corporation, not yet recruiting.","summary":"Evaluate the Safety and Efficacy of BLEX 404 Oral Liquid Combined With Pemetrexed + Cisplatin Therapy is a phase 1/2, interventional study registered as NCT05764928 by Rgene Corporation, with a registry enrolment figure of 32 participants, started 2026-12-01 and due to reach its primary completion in 2027-12-31. Interventions recorded: BLEX 404. Conditions listed: Nonsquamous Nonsmall Cell Neoplasm of Lung. Primary outcome: DLT determination; RDL Determination; Overall response rate (PR + CR) after 4 cycles of combination use. Lung eligibility wording from the registry: \"Naïve patients with histologically or pathologically diagnosed with Advanced Inoperable or Metastatic non-small cell lung cancer and intended for first line treatment\". Sites: Taiwan. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT05764928","url":"https://clinicaltrials.gov/study/NCT05764928"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["egfr-mutant-nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05764928","phase":"1/2","setting":"A Phase I/II, Open Label Study to Evaluate the Safety and Efficacy of BLEX 404Oral Liquid Combined With Pemetrexed + Cisplatin Therapy in Patients With Advanced Inoperable or Metastatic EGFR Wild-type Non-Small Cell Lung Cancer Patients","sponsor":"Rgene Corporation","enrolled":32,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05764928/","neighbours":{"cancer":[{"id":"egfr-mutant-nsclc","kind":"cancer","name":"EGFR-mutated non-small-cell lung cancer","route":"/cancers/egfr-mutant-nsclc/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}