{"entity":{"id":"nct05806931","kind":"trial","name":"Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer","aka":["SCOTI"],"tldr":"A phase 2 trial of bevacizumab (glioblastoma use) in colorectal cancer, run by Rutgers, The State University of New Jersey, now recruiting.","summary":"Sequential TAS-OX Alternating With TAS-IRI Plus Bevacizumab for Late-Line Metastatic Colorectal Cancer is a phase 2, interventional study registered as NCT05806931 by Rutgers, The State University of New Jersey, with a registry enrolment figure of 50 participants, started 2023-05-17 and due to reach its primary completion in 2026-05-01. Interventions recorded: TAS-102, oxaliplatin, irinotecan with bevacizumab. Conditions listed: Colon Cancer; Rectal Cancer. Primary outcome: Disease control rate (DCR):. Colorectal eligibility wording from the registry: \"* Histologically confirmed stage IV colon cancer (AJCC 7th edition) that has progressed after standard therapy that included 5-FU, irinotecan, oxaliplatin and appropriate antibody therapy\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05806931","url":"https://clinicaltrials.gov/study/NCT05806931"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["bevacizumab-glioma"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05806931","phase":"2","setting":"Sequential Combined TAS-102 and Oxaliplatin Alternating With TAS-102 and Irinotecan (Sequential TASOXIRI) With Bevacizumab for Late-Line Metastatic Colorectal Cancer","sponsor":"Rutgers, The State University of New Jersey","enrolled":50,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05806931/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"drug":[{"id":"bevacizumab-glioma","kind":"drug","name":"Bevacizumab (glioblastoma use)","route":"/drugs/bevacizumab-glioma/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}