{"entity":{"id":"nct05810792","kind":"trial","name":"Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer","aka":["PANCEP-1"],"tldr":"A phase 2 trial of histamine dihydrochloride and aldesleukin (high-dose IL-2) in pancreatic cancer, run by Sahlgrenska University Hospital, not yet recruiting.","summary":"Histamine Dihydrochloride and Interleukin-2 in Primary Resectable Pancreatic Cancer is a phase 2, interventional study registered as NCT05810792 by Sahlgrenska University Hospital, with a registry enrolment figure of 50 participants, started 2024-04-01 and due to reach its primary completion in 2027-04-01. Interventions recorded: Histamine Dihydrochloride (HDC); Interleukin-2 (IL-2). Conditions listed: Pancreatic Cancer; Surgery; Metastasis; Immunosuppression. Primary outcome: Incidence and severity of Treatment-Emergent Adverse Events as assessed by NCI-CTCAE. Pancreatic eligibility wording from the registry: \"By the surgeon´s evaluation fit for pancreatic surgery\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05810792","url":"https://clinicaltrials.gov/study/NCT05810792"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["resectable-pdac","metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":["histamine-dihydrochloride","aldesleukin"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05810792","phase":"2","setting":"A Phase I/II Trial of Peri- and Postoperative Treatment With Histamine Dihydrochloride and Low-dose Interleukin-2 in Patients With Primary Resectable Pancreatic Cancer","sponsor":"Sahlgrenska University Hospital","enrolled":50,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05810792/","neighbours":{"cancer":[{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"},{"id":"resectable-pdac","kind":"cancer","name":"Resectable pancreatic ductal adenocarcinoma","route":"/cancers/resectable-pdac/"}],"drug":[{"id":"aldesleukin","kind":"drug","name":"Aldesleukin (high-dose IL-2)","route":"/drugs/aldesleukin/"},{"id":"histamine-dihydrochloride","kind":"drug","name":"Histamine dihydrochloride","route":"/drugs/histamine-dihydrochloride/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}