{"entity":{"id":"nct05841420","kind":"trial","name":"Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients with Non-resectable Pancreatic Cancer","aka":[],"tldr":"A phase 2 trial of gemcitabine and nab-paclitaxel in pancreatic cancer, run by Morten Ladekarl, now recruiting.","summary":"Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients with Non-resectable Pancreatic Cancer is a phase 2, randomised interventional study registered as NCT05841420 by Morten Ladekarl, with a registry enrolment figure of 98 participants, started 2023-06-12 and due to reach its primary completion in 2025-06. Interventions recorded: Gemcitabine; Nab paclitaxel. Conditions listed: Pancreas Cancer; Non-Resectable Pancreas Carcinoma. Primary outcome: PFS (Progression Free Survival). Pancreatic eligibility wording from the registry: \"* Adenocarcinoma of the pancreas, histopathologically or cytologically verified\". Sites: Denmark. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05841420","url":"https://clinicaltrials.gov/study/NCT05841420"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":["gemcitabine","nab-paclitaxel"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05841420","phase":"2","setting":"A Randomized Phase II Study of Gemcitabine Versus Reduced-dose Combination Chemotherapy in Fragile Patients with Non-resectable Pancreatic Cancer","sponsor":"Morten Ladekarl","enrolled":98,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05841420/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"gemcitabine","kind":"drug","name":"Gemcitabine","route":"/drugs/gemcitabine/"},{"id":"nab-paclitaxel","kind":"drug","name":"Nab-paclitaxel","route":"/drugs/nab-paclitaxel/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}