{"entity":{"id":"nct05861505","kind":"trial","name":"COLLISION RELAPSE Trial","aka":[],"tldr":"A phase 3 trial in colorectal cancer, run by Amsterdam UMC, location VUmc, now recruiting.","summary":"COLLISION RELAPSE Trial is a phase 3, randomised interventional study registered as NCT05861505 by Amsterdam UMC, location VUmc, with a registry enrolment figure of 360 participants, started 2023-04-24 and due to reach its primary completion in 2027-05-01. Interventions recorded: Neoadjuvant systemic therapy (CAPOX+/-B FOLFOX+/-B FOLFIRI+/-B); Repeat local treatment. Conditions listed: Colorectal Cancer; Liver Metastases; Liver Metastasis Colon Cancer; Chemotherapy Effect; Surgery; Recurrence. Primary outcome: Overall survival (OS) per patient. Colorectal eligibility wording from the registry: \"* Histological documentation of primary colorectal tumor\". Sites: Netherlands. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT05861505","url":"https://clinicaltrials.gov/study/NCT05861505"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05861505","phase":"3","setting":"COLLISION RELAPSE Trial - Recurrent Colorectal Liver Metastases: Repeat Local Treatment +/- Neoadjuvant Systemic Therapy - a Phase III Prospective Randomized Controlled Trial","sponsor":"Amsterdam UMC, location VUmc","enrolled":360,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05861505/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}