{"entity":{"id":"nct05917405","kind":"trial","name":"Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCT","aka":[],"tldr":"A phase 2 trial of Fludarabine, Busulfan and Clofarabine in Acute myeloid leukaemia, run by Nantes University Hospital, now recruiting.","summary":"Study Comparing the Efficacy of 2 RIC Regimens (Clofarabine vs Fludarabine) in Adults With AML Eligible to Allo-SCT is a phase 2 interventional study registered as NCT05917405 by Nantes University Hospital, with 302 participants planned, started 2023-09-14 and due to reach its primary completion in 2028-09-14. Interventions recorded: Fludarabine, Busulfan, ATG, Clofarabine. Conditions recorded: Acute Myeloid Leukemia in Remission.\n\nLinked to the drug Clofarabine because the registry names it among its interventions and Acute myeloid leukaemia among its conditions. Registry record only: no result has been read by an editor.","status":"recruiting","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT05917405","url":"https://clinicaltrials.gov/study/NCT05917405"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["aml"],"sections":[],"technologies":[],"targets":[],"drugs":["fludarabine","busulfan","clofarabine"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05917405","phase":"2","setting":"FLUCLORIC: Randomized Multicentric Phase III Study Comparing the Efficacy of 2 Reduced Intensity Conditioning Regimens (Clofarabine/Busulfan vs Fludarabine/Busulfan) in Adults With AML and Eligible to Allogeneic Stem Cell Transplantation","sponsor":"Nantes University Hospital","enrolled":302,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05917405/","neighbours":{"cancer":[{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"}],"drug":[{"id":"busulfan","kind":"drug","name":"Busulfan","route":"/drugs/busulfan/"},{"id":"clofarabine","kind":"drug","name":"Clofarabine","route":"/drugs/clofarabine/"},{"id":"fludarabine","kind":"drug","name":"Fludarabine","route":"/drugs/fludarabine/"}]}}