{"entity":{"id":"nct06009029","kind":"trial","name":"SBRT Combined With Zimberelimab (GLS-010) in Locally Advanced Pancreatic Cancer (SPARK-1 Study)","aka":[],"tldr":"A phase 2 trial of zimberelimab in pancreatic cancer, run by Peking University Third Hospital, not yet recruiting.","summary":"SBRT Combined With Zimberelimab (GLS-010) in Locally Advanced Pancreatic Cancer (SPARK-1 Study) is a phase 2, interventional study registered as NCT06009029 by Peking University Third Hospital, with a registry enrolment figure of 96 participants, started 2023-08 and due to reach its primary completion in 2026-07. Interventions recorded: Stereotactic body radiation(SBRT); Zimberelimab (GLS-010). Conditions listed: Locally Advanced Pancreatic Cancer. Primary outcome: Overall survival (OS). Pancreatic eligibility wording from the registry: \"* Locally advanced pancreatic cancer confirmed histologically and defined according to the NCCN Pancreatic Cancer Guidelines v1\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06009029","url":"https://clinicaltrials.gov/study/NCT06009029"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac"],"sections":[],"technologies":["sbrt"],"targets":[],"drugs":["zimberelimab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06009029","phase":"2","setting":"A Multicenter, Single-arm, Prospective Study of SBRT Combined With Zimberelimab (GLS-010) in Patients With Locally Advanced Pancreatic Cancer (SPARK-1 Study)","sponsor":"Peking University Third Hospital","enrolled":96,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06009029/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"}],"technology":[{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"drug":[{"id":"zimberelimab","kind":"drug","name":"Zimberelimab","route":"/drugs/zimberelimab/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}