{"entity":{"id":"nct06041776","kind":"trial","name":"Adjuvant Befotertinib in Stage IB-IIIB Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations","aka":[],"tldr":"A phase 3 trial of Icotinib in non-small-cell lung cancer and small-cell lung cancer, run by Betta Pharmaceuticals Co., Ltd., now recruiting.","summary":"Adjuvant Befotertinib in Stage IB-IIIB Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations is a phase 3 interventional study registered as NCT06041776 by Betta Pharmaceuticals Co., Ltd., with 570 participants planned, started 2023-03-28 and due to reach its primary completion in 2028-04-30. Interventions recorded: Befotertinib + Icotinib placebo, Icotinib + Befotertinib placebo. Conditions listed: Non-Small Cell Lung Cancer, EGFR Sensitive Mutation, Adjuvant Therapy. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06041776","url":"https://clinicaltrials.gov/study/NCT06041776"}],"tags":["ctgov-ingest"],"related":[],"cancers":["nsclc","sclc"],"sections":[],"technologies":[],"targets":[],"drugs":["icotinib"],"companies":["betta"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06041776","phase":"3","setting":"A Multicenter, Randomized, Controlled, Double Blind, Double Simulated, Phase III Clinical Study of Befotertinib vs Icotinib for Postoperative Adjuvant Treatment of IB-IIIB (T3N2M0) Stage Non Small Cell Lung Cancer With Positive EGFR Sensitive Mutations","sponsor":"Betta Pharmaceuticals Co., Ltd.","enrolled":570,"outcomes":[]},"route":"/trials/nct06041776/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"icotinib","kind":"drug","name":"Icotinib","route":"/drugs/icotinib/"}],"company":[{"id":"betta","kind":"company","name":"Betta Pharmaceuticals","route":"/companies/betta/"}]}}