{"entity":{"id":"nct06066424","kind":"trial","name":"Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)","aka":[],"tldr":"An early trial studying the safety and activity of experimental treatment. Its registry status does not establish patient benefit.","summary":"Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA). ClinicalTrials.gov record last updated 2026-10-06: recruiting. Enrollment is planned at 54 participants. Primary completion is estimated at 2038-04-30. No tabular results are posted on ClinicalTrials.gov; this does not exclude separate publications.","status":"recruiting","asOf":"2026-10-06","links":[{"label":"ClinicalTrials.gov NCT06066424","url":"https://clinicaltrials.gov/study/NCT06066424"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":["trop2"],"drugs":["trop2-car-il15-cord-blood-nk"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["ClinicalTrials.gov record last updated 2026-10-06: recruiting. Enrollment is planned at 54 participants. Primary completion is estimated at 2038-04-30. No tabular results are posted on ClinicalTrials.gov; this does not exclude separate publications."],"nct":"NCT06066424","phase":"1","setting":"Phase 1 Dose Escalation and Expansion Study of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells in Patients With Advanced Solid Tumors (TROPIKANA)","sponsor":"M.D. Anderson Cancer Center","started":"2023-10-24","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06066424/","neighbours":{"target":[{"id":"trop2","kind":"target","name":"TROP2","route":"/targets/trop2/"}],"drug":[{"id":"trop2-car-il15-cord-blood-nk","kind":"drug","name":"TROP2 CAR/IL-15 cord-blood NK cells","route":"/drugs/trop2-car-il15-cord-blood-nk/"}]}}