{"entity":{"id":"nct06097416","kind":"trial","name":"Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer","aka":[],"tldr":"A phase 3 trial in colorectal cancer, run by St. James's Hospital, Ireland, not yet recruiting.","summary":"Neoadjuvant Chemoradiotherapy Versus Total Neoadjuvant Therapy in the Treatment of T3 Rectal Cancer is a phase 3, randomised interventional study registered as NCT06097416 by St. James's Hospital, Ireland, with a registry enrolment figure of 100 participants, started 2024-10 and due to reach its primary completion in 2025-10. Interventions recorded: Neoadjuvant Chemoradiotherapy; Total Neoadjuvant Therapy. Conditions listed: Rectal Cancer. Primary outcome: Overall survival. Colorectal eligibility wording from the registry: \"Histologically or cytologically confirmed surgically resectable adenocarcinoma of the rectum\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06097416","url":"https://clinicaltrials.gov/study/NCT06097416"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06097416","phase":"3","setting":"A Phase III, Multi-institutional Randomised Trial Comparing Neoadjuvant Chemoradiotherapy (NARCT) and Total Neoadjuvant Therapy (TNT) in Patients With T3 (a/b/c) Rectal Cancer","sponsor":"St. James's Hospital, Ireland","enrolled":100,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06097416/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}