{"entity":{"id":"nct06154538","kind":"trial","name":"Immune Checkpoint Inhibitors + Chemotherapy Versus Chemotherapy in the Neoadjuvant Treatment of Locally Advanced Colorectal Cancer","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, now recruiting.","summary":"Immune Checkpoint Inhibitors + Chemotherapy Versus Chemotherapy in the Neoadjuvant Treatment of Locally Advanced Colorectal Cancer is a phase 2, randomised interventional study registered as NCT06154538 by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, with a registry enrolment figure of 170 participants, started 2023-11-01 and due to reach its primary completion in 2026-11-01. Interventions recorded: Immune checkpoint inhibitor; FOLFOX regimen. Conditions listed: Locally Advanced Colorectal Carcinoma. Primary outcome: pCR rate. Colorectal eligibility wording from the registry: \"* Histologically or cytologically confirmed colorectal adenocarcinoma;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06154538","url":"https://clinicaltrials.gov/study/NCT06154538"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06154538","phase":"2","setting":"Comparison of Immune Checkpint Inhibitors Combined With Chemotherapy Versus Chemotherapy Alone in the Neoadjuvant Treatment of Locally Advanced Colorectal Cancer: a Randomized, Open-label, Single-center Phase II Clinical Study","sponsor":"Cancer Institute and Hospital, Chinese Academy of Medical Sciences","enrolled":170,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06154538/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}