{"entity":{"id":"nct06162650","kind":"trial","name":"Total Neoadjuvant Therapy in Rectal Cancer","aka":[],"tldr":"A phase 2 trial of fOLFOX (5-FU, leucovorin, oxaliplatin) in colorectal cancer, run by National Cheng-Kung University Hospital, now recruiting.","summary":"Total Neoadjuvant Therapy in Rectal Cancer is a phase 2, interventional study registered as NCT06162650 by National Cheng-Kung University Hospital, with a registry enrolment figure of 42 participants, started 2023-11-16 and due to reach its primary completion in 2026-11-16. Interventions recorded: Short-course radiotherapy; mFOLFOX6. Conditions listed: Rectal Cancer. Primary outcome: Complete response (CR) rate. Colorectal eligibility wording from the registry: \"* Histologically confirmed diagnosis of adenocarcinoma of the rectum;\". Sites: Taiwan. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06162650","url":"https://clinicaltrials.gov/study/NCT06162650"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["cytotoxic-chemotherapy","imrt-igrt","platinum"],"targets":[],"drugs":["folfox"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06162650","phase":"2","setting":"A Phase II Study of Total Neoadjuvant Therapy in Rectal Cancer","sponsor":"National Cheng-Kung University Hospital","enrolled":42,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06162650/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"},{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"},{"id":"platinum","kind":"technology","name":"Platinum agents","route":"/technologies/platinum/"}],"drug":[{"id":"folfox","kind":"drug","name":"FOLFOX (5-FU, leucovorin, oxaliplatin)","route":"/drugs/folfox/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}