{"entity":{"id":"nct06202001","kind":"trial","name":"Irinotecan, TAS-102 Plus Bevacizumab as a Second-Line Therapy in mCRC Patients","aka":[],"tldr":"A phase 1/2 trial in colorectal cancer, run by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, now recruiting.","summary":"Irinotecan, TAS-102 Plus Bevacizumab as a Second-Line Therapy in mCRC Patients is a phase 1/2, interventional study registered as NCT06202001 by Cancer Institute and Hospital, Chinese Academy of Medical Sciences, with a registry enrolment figure of 70 participants, started 2022-10-01 and due to reach its primary completion in 2025-09-30. Interventions recorded: Irinotecan, Trifluridine/tipiracil (TAS-102) plus Bevacizumab. Conditions listed: Metastatic Colorectal Cancer. Primary outcome: Objective Response Rate (ORR). Colorectal eligibility wording from the registry: \"Colorectal adenocarcinoma confirmed histologically or histopathologically\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06202001","url":"https://clinicaltrials.gov/study/NCT06202001"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06202001","phase":"1/2","setting":"Phase I/II Study of Irinotecan Plus Trifluridine/Tipiracil (TAS-102) in Combination With Bevacizumab as a Second-Line Therapy for Patients With Metastatic Colorectal Cancer (mCRC)","sponsor":"Cancer Institute and Hospital, Chinese Academy of Medical Sciences","enrolled":70,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06202001/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}