{"entity":{"id":"nct06218810","kind":"trial","name":"Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal","aka":[],"tldr":"A phase 2 trial in colorectal cancer, run by Fudan University, now recruiting.","summary":"Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer is a phase 2, interventional study registered as NCT06218810 by Fudan University, with a registry enrolment figure of 53 participants, started 2024-01-01 and due to reach its primary completion in 2025-12-31. Interventions recorded: Cadonilimab + bevacizumab + FOLFOX. Conditions listed: Metastatic Colorectal Cancer; Microsatellite Stable Colorectal Carcinoma; RAS Mutation; Cadonilimab. Primary outcome: 1-year Progression Free Survival rate. Colorectal eligibility wording from the registry: \"Subjects diagnosed with metastatic colorectal adenocarcinoma by histology or cytology\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06218810","url":"https://clinicaltrials.gov/study/NCT06218810"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06218810","phase":"2","setting":"Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer: A Single-Arm, Open-Label, Multicenter Phase II Study","sponsor":"Fudan University","enrolled":53,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06218810/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}