{"entity":{"id":"nct06220032","kind":"trial","name":"Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma","aka":[],"tldr":"A phase 3 trial of Dexrazoxane, Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone, Lenalidomide and Pegfilgrastim in Diffuse large B-cell lymphoma, run by Stichting Hemato-Oncologie voor Volwassenen Nederland, now recruiting.","summary":"Prevention of Anthracycline-Induced Cardiac Dysfunction With Dexrazoxane in Patients With Diffuse Large-B Cell Lymphoma is a phase 3 interventional study registered as NCT06220032 by Stichting Hemato-Oncologie voor Volwassenen Nederland, with 324 participants planned, started 2024-08-15 and due to reach its primary completion in 2028-12-15. Interventions recorded: Dexrazoxane, Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone, Lenalidomide, Pegfilgrastim. Conditions recorded: DLBCL - Diffuse Large B Cell Lymphoma.\n\nLinked to the drug Dexrazoxane because the registry names it among its interventions and Diffuse large B-cell lymphoma among its conditions. Registry record only: no result has been read by an editor.","status":"recruiting","asOf":"2026-09-22","links":[{"label":"ClinicalTrials.gov NCT06220032","url":"https://clinicaltrials.gov/study/NCT06220032"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["dlbcl"],"sections":[],"technologies":[],"targets":[],"drugs":["dexrazoxane","rituximab","cyclophosphamide","doxorubicin","vincristine","prednisone","lenalidomide","pegfilgrastim"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06220032","phase":"3","setting":"ANTICIPATE: Prevention of ANThracycline-Induced Cardiac Dysfunction by Dexrazoxane In PATients With diffusE Large B-cell Lymphoma: a Phase III National Multicenter Prospective Randomized Open-label Trial","sponsor":"Stichting Hemato-Oncologie voor Volwassenen Nederland","enrolled":324,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06220032/","neighbours":{"cancer":[{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"}],"drug":[{"id":"cyclophosphamide","kind":"drug","name":"Cyclophosphamide","route":"/drugs/cyclophosphamide/"},{"id":"dexrazoxane","kind":"drug","name":"Dexrazoxane","route":"/drugs/dexrazoxane/"},{"id":"doxorubicin","kind":"drug","name":"Doxorubicin","route":"/drugs/doxorubicin/"},{"id":"lenalidomide","kind":"drug","name":"Lenalidomide","route":"/drugs/lenalidomide/"},{"id":"pegfilgrastim","kind":"drug","name":"Pegfilgrastim","route":"/drugs/pegfilgrastim/"},{"id":"prednisone","kind":"drug","name":"Prednisone","route":"/drugs/prednisone/"},{"id":"rituximab","kind":"drug","name":"Rituximab","route":"/drugs/rituximab/"},{"id":"vincristine","kind":"drug","name":"Vincristine","route":"/drugs/vincristine/"}]}}