{"entity":{"id":"nct06225284","kind":"trial","name":"Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients","aka":["ESCALATE"],"tldr":"A phase 2 trial in triple-negative breast cancer, run by National Taiwan University Hospital, now recruiting.","summary":"Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients is a phase 2, randomised interventional study registered as NCT06225284 by National Taiwan University Hospital, with a registry enrolment figure of 124 participants, started 2024-08-22 and due to reach its primary completion in 2026-12. Interventions recorded: Goserelin Acetate 3.6mg、Goserelin Acetate 10.8mg、Leuprolide Acetate 3.75mg、Leuprorelin Acetate 22.5mg、Triptorelin pamoate 11.25mg、Triptorelin pamoate 22.5mg. Conditions listed: Triple Negative Breast Cancer; Premenopausal Breast Cancer. Triple-negative eligibility wording from the registry: \"Histological confirmed TNBC, as defined by the most recent ASCO/CAP guidelines\". Sites: Taiwan. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06225284","url":"https://clinicaltrials.gov/study/NCT06225284"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-early"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06225284","phase":"2","setting":"A Randomized Phase II Study of Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients: ESCALATE Study","sponsor":"National Taiwan University Hospital","enrolled":124,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06225284/","neighbours":{"cancer":[{"id":"tnbc-early","kind":"cancer","name":"Early triple-negative breast cancer","route":"/cancers/tnbc-early/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}