{"entity":{"id":"nct06226857","kind":"trial","name":"Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer","aka":["CRC01"],"tldr":"A phase 3 trial of cetuximab in colorectal cancer, run by City Clinical Oncology Hospital No 1, now recruiting.","summary":"Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer is a phase 3, randomised interventional study registered as NCT06226857 by City Clinical Oncology Hospital No 1, with a registry enrolment figure of 355 participants, started 2024-01-17 and due to reach its primary completion in 2026-12-31. Interventions recorded: Cetuximab. Conditions listed: Colorectal Neoplasms; Chemotherapy Effect; Molecular Sequence Variation. Primary outcome: progression-free survival. Colorectal eligibility wording from the registry: \"Verified diagnosis of colorectal adenocarcinoma (C18\". Sites: Russia. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06226857","url":"https://clinicaltrials.gov/study/NCT06226857"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["monoclonal-antibody"],"targets":[],"drugs":["cetuximab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06226857","phase":"3","setting":"Predictive Value of Other Oncogene Mutations for Anti-EGFR Monoclonal Antibodies Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer: Multicenter Randomized Phase III Trial","sponsor":"City Clinical Oncology Hospital No 1","enrolled":355,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06226857/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"monoclonal-antibody","kind":"technology","name":"Monoclonal antibodies","route":"/technologies/monoclonal-antibody/"}],"drug":[{"id":"cetuximab","kind":"drug","name":"Cetuximab","route":"/drugs/cetuximab/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}