{"entity":{"id":"nct06243393","kind":"trial","name":"Sacituzumab Govitecan in Metastatic Colorectal Cancer","aka":["TROPHIT1"],"tldr":"A phase 2/3 trial of sacituzumab govitecan in colorectal cancer, run by University Hospital Heidelberg, now recruiting.","summary":"Sacituzumab Govitecan in Metastatic Colorectal Cancer is a phase 2/3, randomised interventional study registered as NCT06243393 by University Hospital Heidelberg, with a registry enrolment figure of 80 participants, started 2024-04-19 and due to reach its primary completion in 2028-08-01. Interventions recorded: Sacituzumab Govitecan (SG); Physicians Choice (PhC).. Conditions listed: Metastatic Colorectal Cancer. Primary outcome: Progression Free Survival (PFS). Colorectal eligibility wording from the registry: \"Permanent sterilization methods include hysterectomy, bilateral salpingectomy and bilateral oophorectomy\". Sites: Germany. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06243393","url":"https://clinicaltrials.gov/study/NCT06243393"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["adc"],"targets":[],"drugs":["sacituzumab-govitecan"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06243393","phase":"2/3","setting":"A Randomized, Open Label, Multicenter Phase II/III Trial of Sacituzumab Govitecan Compared to Standard of Care in Metastatic, Refractory Colorectal Cancer Patients","sponsor":"University Hospital Heidelberg","enrolled":80,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06243393/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"adc","kind":"technology","name":"Antibody-drug conjugate (ADC)","route":"/technologies/adc/"}],"drug":[{"id":"sacituzumab-govitecan","kind":"drug","name":"Sacituzumab govitecan","route":"/drugs/sacituzumab-govitecan/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}