{"entity":{"id":"nct06254599","kind":"trial","name":"A Study Of SY-3505 Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC","aka":[],"tldr":"A phase 3 trial in lung cancer, run by Shouyao Holdings (Beijing) Co. LTD, not yet recruiting.","summary":"A Study Of SY-3505 Versus Crizotinib In First Line Treatment Of Patients With ALK-Positive NSCLC is a phase 3, randomised interventional study registered as NCT06254599 by Shouyao Holdings (Beijing) Co. LTD, with a registry enrolment figure of 255 participants, started 2024-05-01 and due to reach its primary completion in 2026-05-01. Interventions recorded: SY-3505 Capsules; Crizotinib Capsules. Conditions listed: Non-small Cell Lung Cancer. Primary outcome: Progression-free survival (PFS) assessed by independent radiology review (IRC) based on Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1 (v1.1) criteria.. Lung eligibility wording from the registry: \"Histologically or cytologically diagnosed with stage IV or stage IIIB and IIIC NSCLC that cannot be cured by surgery or radiotherapy (as per the 8th edition of the International Association for the Study of Lung Cancer \\[IASLC\\] Lung Cancer Staging)\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT06254599","url":"https://clinicaltrials.gov/study/NCT06254599"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["alk-positive-nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06254599","phase":"3","setting":"A Phase III Study to Evaluate and Compare the Efficacy and Safety of SY-3505 Versus Crizotinib in Treatment-Naive Patients With Anaplastic Lymphoma Kinase (ALK)-Positive Advanced Non-Small Cell Lung Cancer","sponsor":"Shouyao Holdings (Beijing) Co. LTD","enrolled":255,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06254599/","neighbours":{"cancer":[{"id":"alk-positive-nsclc","kind":"cancer","name":"ALK-positive non-small-cell lung cancer","route":"/cancers/alk-positive-nsclc/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}