{"entity":{"id":"nct06307548","kind":"trial","name":"Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurre","aka":[],"tldr":"A phase 1/2 trial in colorectal cancer, run by Roswell Park Cancer Institute, now recruiting.","summary":"Fluorescence Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Locally Advanced or Recurrent Colorectal Cancer is a phase 1/2, interventional study registered as NCT06307548 by Roswell Park Cancer Institute, with a registry enrolment figure of 21 participants, started 2024-07-30 and due to reach its primary completion in 2027-06-01. Interventions recorded: Aminolevulinic Acid; Biospecimen Collection; Computed Tomography; Fluorescence-Guided Surgery; Magnetic Resonance Imaging; Photodynamic Therapy; Surgical Procedure. Conditions listed: Locally Advanced Colorectal Carcinoma; Recurrent Colorectal Carcinoma; Stage III Colorectal Cancer. Primary outcome: Accuracy of the fluorescence imaging (Phase I); Incidence of adverse events (Phase I); Evidence of disease (Phase II). Colorectal eligibility wording from the registry: \"* Patients with locally advanced or recurrent colorectal cancer undergoing surgery\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06307548","url":"https://clinicaltrials.gov/study/NCT06307548"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06307548","phase":"1/2","setting":"Image Guided Surgery Followed by Intraoperative Photodynamic Therapy for Improving Local Tumor Control in Patients With Loco-Regionally Advanced or Recurrent Colorectal Cancer Undergoing Surgery - Phase I/II","sponsor":"Roswell Park Cancer Institute","enrolled":21,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06307548/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}