{"entity":{"id":"nct06319313","kind":"trial","name":"Efficacy and Safety of JMT101 Combined Wth Docetaxel / HB1801 in Patients With Squamous Cell Non-Small Cell Lung Cancer","aka":[],"tldr":"A phase 2/3 trial of JMT101, docetaxel and HB1801 in lung cancer, run by Shanghai JMT-Bio Inc., not yet recruiting.","summary":"Efficacy and Safety of JMT101 Combined Wth Docetaxel / HB1801 in Patients With Squamous Cell Non-Small Cell Lung Cancer is a phase 2/3, randomised interventional study registered as NCT06319313 by Shanghai JMT-Bio Inc., with a registry enrolment figure of 534 participants, started 2024-05-01 and due to reach its primary completion in 2026-07-01. Interventions recorded: JMT101; docetaxel; HB1801. Conditions listed: Squamous Cell Non-small Cell Lung Cancer. Primary outcome: Overall response rate (ORR); Overall Survival (OS); Incidence and severity of adverse events (AE) and serious adverse events (SAE). Lung eligibility wording from the registry: \"Pathological diagnosis as sqNSCLC, with EGFR highly expressed, without other driver genes\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT06319313","url":"https://clinicaltrials.gov/study/NCT06319313"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["lung-squamous-cell-carcinoma"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":["jmt101","docetaxel","hb1801"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06319313","phase":"2/3","setting":"A Randomized, Controlled, Open-label Phase II/III Study of The Safety, Tolerability and Efficacy of JMT101 Combined With Docetaxel / HB1801 in Patients With sqNSCLC","sponsor":"Shanghai JMT-Bio Inc.","enrolled":534,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06319313/","neighbours":{"cancer":[{"id":"lung-squamous-cell-carcinoma","kind":"cancer","name":"Squamous cell carcinoma of the lung","route":"/cancers/lung-squamous-cell-carcinoma/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"drug":[{"id":"docetaxel","kind":"drug","name":"Docetaxel","route":"/drugs/docetaxel/"},{"id":"hb1801","kind":"drug","name":"HB1801","route":"/drugs/hb1801/"},{"id":"jmt101","kind":"drug","name":"JMT101","route":"/drugs/jmt101/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}