{"entity":{"id":"nct06349590","kind":"trial","name":"Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery","aka":["DIET"],"tldr":"A phase 1/2 trial in colorectal cancer, run by University of Chicago, now recruiting.","summary":"Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery is a phase 1/2, interventional study registered as NCT06349590 by University of Chicago, with a registry enrolment figure of 80 participants, started 2024-06-27 and due to reach its primary completion in 2026-04-06. Interventions recorded: High-fiber/low-fat meals. Conditions listed: Colorectal Cancer. Primary outcome: Change in lab values of the dietary intervention on the collagenolytic potential of the microenvironment.. Colorectal eligibility wording from the registry: \"* Must have histologically or cytologically confirmed colorectal adenocarcinoma\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06349590","url":"https://clinicaltrials.gov/study/NCT06349590"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06349590","phase":"1/2","setting":"A Phase 1/2 Study of Manipulation of the Gut Microbiome by a Standardized Preoperative Diet to Prevent Colorectal Cancer Recurrence and Metastasis Following Surgery (The DIET Trial)","sponsor":"University of Chicago","enrolled":80,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06349590/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}