{"entity":{"id":"nct06365788","kind":"trial","name":"Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer","aka":["ABBICAR"],"tldr":"A phase 2 trial of abemaciclib and bicalutamide in triple-negative breast cancer, run by Universitaire Ziekenhuizen KU Leuven, now recruiting.","summary":"Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer is a phase 2, interventional study registered as NCT06365788 by Universitaire Ziekenhuizen KU Leuven, with a registry enrolment figure of 53 participants, started 2024-04-08 and due to reach its primary completion in 2027-12. Interventions recorded: Abemaciclib; Bicalutamide. Conditions listed: Triple Negative Breast Neoplasms. Triple-negative eligibility wording from the registry: \"The patient has a biopsy-confirmed diagnosis of recurrent, unresectable, locally advanced, or metastatic AR+ TNBC\". Sites: Belgium. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06365788","url":"https://clinicaltrials.gov/study/NCT06365788"}],"tags":["ctgov-ingest","tnbc-deep-dive"],"related":[],"cancers":["tnbc-early","tnbc-metastatic"],"sections":[],"technologies":[],"targets":[],"drugs":["abemaciclib","bicalutamide"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06365788","phase":"2","setting":"A Multicenter Single Arm Phase II Study With Bicalutamide in Combination With Abemaciclib in 4 Cohorts of Locoregionally Advanced Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer","sponsor":"Universitaire Ziekenhuizen KU Leuven","enrolled":53,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06365788/","neighbours":{"cancer":[{"id":"tnbc-early","kind":"cancer","name":"Early triple-negative breast cancer","route":"/cancers/tnbc-early/"},{"id":"tnbc-metastatic","kind":"cancer","name":"Metastatic triple-negative breast cancer","route":"/cancers/tnbc-metastatic/"}],"drug":[{"id":"abemaciclib","kind":"drug","name":"Abemaciclib","route":"/drugs/abemaciclib/"},{"id":"bicalutamide","kind":"drug","name":"Bicalutamide","route":"/drugs/bicalutamide/"}],"term":[{"id":"tnbc-trials-open-today","kind":"term","name":"Triple-negative breast cancer trials open today (registry snapshot and UK sites)","route":"/terms/tnbc-trials-open-today/"}]}}