{"entity":{"id":"nct06373133","kind":"trial","name":"SHR-8068 Combined With Adbelizumab and BP102 in the Treatment of Advanced Colorectal Cancer","aka":[],"tldr":"A phase 1/2 trial of SHR-8068 and adebrelimab in colorectal cancer, run by West China Hospital, not yet recruiting.","summary":"SHR-8068 Combined With Adbelizumab and BP102 in the Treatment of Advanced Colorectal Cancer is a phase 1/2, interventional study registered as NCT06373133 by West China Hospital, with a registry enrolment figure of 36 participants, started 2024-05-01 and due to reach its primary completion in 2026-11-01. Interventions recorded: SHR-8068; Adebrelimab; BP102. Conditions listed: Colorectal Cancer. Primary outcome: Dose-limiting toxicity; PFS. Colorectal eligibility wording from the registry: \"pathologically confirmed metastatic colorectal adenocarcinoma;\". No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06373133","url":"https://clinicaltrials.gov/study/NCT06373133"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["checkpoint-inhibitor"],"targets":[],"drugs":["shr-8068","adebrelimab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06373133","phase":"1/2","setting":"An Exploratory Clinical Trial of SHR-8068 Combined With Aldebelizumab and BP102 in the Treatment of Refractory Colorectal Cancer","sponsor":"West China Hospital","enrolled":36,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06373133/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"checkpoint-inhibitor","kind":"technology","name":"Immune checkpoint inhibitors","route":"/technologies/checkpoint-inhibitor/"}],"drug":[{"id":"adebrelimab","kind":"drug","name":"Adebrelimab","route":"/drugs/adebrelimab/"},{"id":"shr-8068","kind":"drug","name":"SHR-8068","route":"/drugs/shr-8068/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}