{"entity":{"id":"nct06399757","kind":"trial","name":"A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of APL-5125 in colorectal cancer, biliary tract cancer, appendiceal cancer and pseudomyxoma peritonei, pancreatic ductal adenocarcinoma, gastric & gastro-oesophageal junction cancer and endometrial cancer, run by Apollo Therapeutics Ltd, active and no longer recruiting.","summary":"A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06399757 by Apollo Therapeutics Ltd, with 100 participants enrolled, started 2024-06-18 and due to reach its primary completion in 2027-04. Interventions recorded: APL-5125.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06399757","url":"https://clinicaltrials.gov/study/NCT06399757"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["colorectal","cholangiocarcinoma","appendiceal","pancreatic","gastric","endometrial"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06399757","phase":"1/2","setting":"A Phase 1/2 Study to Assess the Safety and Antitumor Activity of APL-5125 in Adults With Selected Advanced Solid Tumors","sponsor":"Apollo Therapeutics Ltd","enrolled":100,"outcomes":[]},"route":"/trials/nct06399757/","neighbours":{"cancer":[{"id":"appendiceal","kind":"cancer","name":"Appendiceal cancer and pseudomyxoma peritonei","route":"/cancers/appendiceal/"},{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}]}}