{"entity":{"id":"nct06401824","kind":"trial","name":"Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases","aka":[],"tldr":"A phase 2 trial of bevacizumab in lung cancer, run by Maastricht University Medical Center, now recruiting.","summary":"Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases is a phase 2, interventional study registered as NCT06401824 by Maastricht University Medical Center, with a registry enrolment figure of 25 participants, started 2025-04-24 and due to reach its primary completion in 2026-11-01. Interventions recorded: Sacituzumab Govitecan-Hziy 180 MG plus bevacizumab. Conditions listed: NSCLC Stage IV; Brain Metastases, Adult. Primary outcome: brain metastases overall response rate (ORR). Lung eligibility wording from the registry: \"Pathology proven metastatic non-squamous NSCLC\". Sites: Netherlands. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT06401824","url":"https://clinicaltrials.gov/study/NCT06401824"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":["antiangiogenic","monoclonal-antibody"],"targets":[],"drugs":["bevacizumab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06401824","phase":"2","setting":"A Single Arm Phase II Study Evaluating Intracranial Efficacy of Sacituzumab Govitecan (SG) With Bevacizumab in Patients With Active, Asymptomatic Brain Metastases From Non-small Cell Lung Cancer (NSCLC)","sponsor":"Maastricht University Medical Center","enrolled":25,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06401824/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"technology":[{"id":"antiangiogenic","kind":"technology","name":"Anti-angiogenic therapy","route":"/technologies/antiangiogenic/"},{"id":"monoclonal-antibody","kind":"technology","name":"Monoclonal antibodies","route":"/technologies/monoclonal-antibody/"}],"drug":[{"id":"bevacizumab","kind":"drug","name":"Bevacizumab","route":"/drugs/bevacizumab/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}