{"entity":{"id":"nct06440902","kind":"trial","name":"Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA","aka":[],"tldr":"A phase 2 trial of cetuximab in colorectal cancer, run by Fudan University, now recruiting.","summary":"Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA is a phase 2, interventional study registered as NCT06440902 by Fudan University, with a registry enrolment figure of 1100 participants, started 2023-12-28 and due to reach its primary completion in 2028-09-01. Interventions recorded: Cetuximab. Conditions listed: Colorectal Cancer Metastatic. Primary outcome: Detection rate of NeoRAS WT. Colorectal eligibility wording from the registry: \"Metastatic colorectal cancer with tissue RAS mutation-type;\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06440902","url":"https://clinicaltrials.gov/study/NCT06440902"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":["monoclonal-antibody","mrd-testing"],"targets":[],"drugs":["cetuximab"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06440902","phase":"2","setting":"Exploration of Therapeutic Strategies for NeoRAS Wild-type Metastatic Colorectal Cancer Based on Circulating Tumor DNA: an Open, Prospective, Phase II Study","sponsor":"Fudan University","enrolled":1100,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06440902/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"monoclonal-antibody","kind":"technology","name":"Monoclonal antibodies","route":"/technologies/monoclonal-antibody/"},{"id":"mrd-testing","kind":"technology","name":"MRD / molecular residual disease testing","route":"/technologies/mrd-testing/"}],"drug":[{"id":"cetuximab","kind":"drug","name":"Cetuximab","route":"/drugs/cetuximab/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}