{"entity":{"id":"nct06445738","kind":"trial","name":"PROSPECTIVE radiotherapy omission","aka":["Post-operative Radiotherapy Omission in Selected Patients With Early Breast Cancer Trial International VErsion (PROSPECTIVE)"],"tldr":"PROSPECTIVE uses MRI and other selection criteria to identify people who may omit radiation after breast surgery. It follows whether cancer returns in the same breast.","summary":"PROSPECTIVE uses MRI and other selection criteria to identify people who may omit radiation after breast surgery. It follows whether cancer returns in the same breast.\n\nInterventional study registered as NCT06445738, sponsored by Breast Cancer Trials, Australia and New Zealand. No drug-development phase applies in the structured registry record. Registry enrollment is 1,400 participants (estimated). Registry status checked October 10, 2026: recruiting. UCSF lists this study as closed to local enrollment; local availability and overall registry status are separate. See the registry for full eligibility and current sites.","status":"recruiting","asOf":"2026-10-10","links":[{"label":"ClinicalTrials.gov NCT06445738","url":"https://clinicaltrials.gov/study/NCT06445738"},{"label":"UCSF study listing and local availability","url":"https://clinicaltrials.ucsf.edu/trial/NCT06445738"}],"tags":["ucsf-breast-coverage","interventional"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["ucsf"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06445738","phase":"not-applicable","setting":"Selected early breast cancer after breast-conserving surgery","sponsor":"Breast Cancer Trials, Australia and New Zealand","participation":[{"nct":"NCT06445738","source":"https://clinicaltrials.gov/study/NCT06445738","fetchedAt":"2026-10-10T20:54:22.098278Z","studySha256":"45b2e0625d59346a3ccf29c5a6356a32d0d892d291724b8f6d3a8fecd5895538","overallStatus":"RECRUITING","lastUpdatePosted":"2026-01-15","leadSponsor":"Breast Cancer Trials, Australia and New Zealand","collaboratorCount":0,"minimumAge":"50 Years","sex":"FEMALE","healthyVolunteers":false,"hasEligibility":true,"enrolment":1400,"enrolmentType":"ESTIMATED","siteCount":9,"recruitingSiteCount":3,"countries":["Australia","United States"]}],"started":"2025-06-06","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06445738/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"institution":[{"id":"ucsf","kind":"institution","name":"UCSF Helen Diller Family Comprehensive Cancer Center","route":"/institutions/ucsf/"}]}}