{"entity":{"id":"nct06463028","kind":"trial","name":"Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial ","aka":[],"tldr":"A phase 2 trial of Sapanisertib, Serabelisib, Paclitaxel / nab-paclitaxel in endometrial cancer, run by Faeth Therapeutics, now recruiting.","summary":"Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer is a phase 2 interventional study registered as NCT06463028 by Faeth Therapeutics, with 40 participants planned, started 2024-12-12 and due to reach its primary completion in 2028-09. Interventions recorded: Sapanisertib, Serabelisib, Paclitaxel. Conditions listed: Endometrial Cancer. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06463028","url":"https://clinicaltrials.gov/study/NCT06463028"}],"tags":["ctgov-ingest"],"related":[],"cancers":["endometrial"],"sections":[],"technologies":[],"targets":[],"drugs":["sapanisertib","serabelisib","paclitaxel"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06463028","phase":"2","setting":"An Open-label, Multi-Center, Phase 2 Clinical Trial Evaluating Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel, and a Substudy Evaluating PIKTOR With Paclitaxel Plus an Insulin-Suppressing Diet, in Patients With Advanced or Recurrent Endometrial Cancer","sponsor":"Faeth Therapeutics","enrolled":40,"outcomes":[]},"route":"/trials/nct06463028/","neighbours":{"cancer":[{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"}],"drug":[{"id":"paclitaxel","kind":"drug","name":"Paclitaxel / nab-paclitaxel","route":"/drugs/paclitaxel/"},{"id":"sapanisertib","kind":"drug","name":"Sapanisertib","route":"/drugs/sapanisertib/"},{"id":"serabelisib","kind":"drug","name":"Serabelisib","route":"/drugs/serabelisib/"}]}}