{"entity":{"id":"nct06479239","kind":"trial","name":"Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer","aka":["Panc 002"],"tldr":"A phase 1/2 trial in pancreatic cancer, run by University of Virginia, now recruiting.","summary":"Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer is a phase 1/2, interventional study registered as NCT06479239 by University of Virginia, with a registry enrolment figure of 23 participants, started 2024-11-06 and due to reach its primary completion in 2027-12. Interventions recorded: EGFR FPBMC. Conditions listed: Pancreas Cancer; Pancreatic Cancer. Primary outcome: Dose limiting toxicities (DLTs) during the dose escalation phase (during the first 8 infusions only). Pancreatic eligibility wording from the registry: \"Histologically confirmed locally advanced pancreatic cancer (LAPC)/unresectable pancreatic cancer (UPC) or metastatic pancreatic cancer (MPC) not eligible for curative intent therapy\". Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06479239","url":"https://clinicaltrials.gov/study/NCT06479239"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["locally-advanced-pdac","metastatic-pdac"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06479239","phase":"1/2","setting":"Phase I/II Study of Anti-CD3 x Anti-EGFR Bispecific Antibody (EGFRBi) Armed Fresh Peripheral Blood Mononuclear Cells (EGFR FPBMC) in Metastatic or Unresectable Pancreatic Cancer","sponsor":"University of Virginia","enrolled":23,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06479239/","neighbours":{"cancer":[{"id":"locally-advanced-pdac","kind":"cancer","name":"Locally advanced unresectable pancreatic ductal adenocarcinoma","route":"/cancers/locally-advanced-pdac/"},{"id":"metastatic-pdac","kind":"cancer","name":"Metastatic pancreatic ductal adenocarcinoma","route":"/cancers/metastatic-pdac/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}