{"entity":{"id":"nct06496048","kind":"trial","name":"Lurbinectedin or in Combination with Irinotecan Versus Topotecan in Patients with Relapsed SCLC","aka":[],"tldr":"A phase 3 trial of Lurbinectedin, FOLFIRI, Topotecan in small-cell lung cancer, run by Luye Pharma Group Ltd., now recruiting.","summary":"Lurbinectedin or in Combination with Irinotecan Versus Topotecan in Patients with Relapsed SCLC is a phase 3 interventional study registered as NCT06496048 by Luye Pharma Group Ltd., with 180 participants planned, started 2024-09-14 and due to reach its primary completion in 2027-12-31. Interventions recorded: Lurbinectedin, Irinotecan, Lurbinectedin, Topotecan. Conditions listed: Relapsed Small Cell Lung Cancer. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06496048","url":"https://clinicaltrials.gov/study/NCT06496048"}],"tags":["ctgov-ingest"],"related":[],"cancers":["sclc"],"sections":[],"technologies":[],"targets":[],"drugs":["lurbinectedin","folfiri","topotecan"],"companies":["luye-pharma"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06496048","phase":"3","setting":"A Phase III, Multicenter, Randomized, Open-label Study of Lurbinectedin As Monotherapy or in Combination with Irinotecan Versus Topotecan in Patients with Relapsed Small-cell Lung Cancer (SCLC)","sponsor":"Luye Pharma Group Ltd.","enrolled":180,"outcomes":[]},"route":"/trials/nct06496048/","neighbours":{"cancer":[{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"folfiri","kind":"drug","name":"FOLFIRI (5-FU, leucovorin, irinotecan)","route":"/drugs/folfiri/"},{"id":"lurbinectedin","kind":"drug","name":"Lurbinectedin","route":"/drugs/lurbinectedin/"},{"id":"topotecan","kind":"drug","name":"Topotecan","route":"/drugs/topotecan/"}],"company":[{"id":"luye-pharma","kind":"company","name":"Luye Pharma Group","route":"/companies/luye-pharma/"}]}}