{"entity":{"id":"nct06501196","kind":"trial","name":"A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome","aka":[],"tldr":"A phase 1 trial of BH-30236 run by BlossomHill Therapeutics, now recruiting.","summary":"A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome is a phase 1 interventional study registered as NCT06501196 by BlossomHill Therapeutics, with 170 participants planned, started 2024-06-19. Conditions recorded: Leukemia, Leukemia, Myeloid, Leukemia, Myeloid, Acute, Preleukemia, Myelodysplastic Syndromes and Refractory Acute Myeloid Leukemia. Interventions recorded: BH-30236 and Venetoclax.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT06501196","url":"https://clinicaltrials.gov/study/NCT06501196"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["leukaemia","aml","mds"],"sections":[],"technologies":[],"targets":[],"drugs":["bh-30236"],"companies":["blossomhill-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06501196","phase":"1","setting":"A Phase 1/1b Open-Label, Dose Escalation, First-in- Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-leukemic Activity of the Orally Available CDC-Like Kinase (CLK) Inhibitor, BH-30236, in Adults With Relapsed or Refractory Acute Myelogenous Leukemia (R/R AML) or Higher-Risk Myelodysplastic Syndrome (HR-MDS)","sponsor":"BlossomHill Therapeutics","enrolled":170,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06501196/","neighbours":{"cancer":[{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"},{"id":"leukaemia","kind":"cancer","name":"Leukaemia (all types)","route":"/cancers/leukaemia/"},{"id":"mds","kind":"cancer","name":"Myelodysplastic syndromes / neoplasms (MDS)","route":"/cancers/mds/"}],"drug":[{"id":"bh-30236","kind":"drug","name":"BH-30236","route":"/drugs/bh-30236/"}],"company":[{"id":"blossomhill-therapeutics","kind":"company","name":"BlossomHill Therapeutics","route":"/companies/blossomhill-therapeutics/"}]}}