{"entity":{"id":"nct06501482","kind":"trial","name":"Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI","aka":["IRIMAD"],"tldr":"A phase 3 trial in colorectal cancer, run by Assistance Publique - Hôpitaux de Paris, now recruiting.","summary":"Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI is a phase 3, randomised interventional study registered as NCT06501482 by Assistance Publique - Hôpitaux de Paris, with a registry enrolment figure of 254 participants, started 2025-06-27 and due to reach its primary completion in 2028-06-27. Interventions recorded: Postoperative reintroduction of FOLFIRI based chemotherapy. Conditions listed: Colorectal Cancer; Colorectal Liver Metastases. Primary outcome: The disease-free survival rate. Colorectal eligibility wording from the registry: \"For this study, metachronous CLM is defined as liver recurrence occurring more than 12 months after treatment of the primary colorectal cancer\". Sites: France. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06501482","url":"https://clinicaltrials.gov/study/NCT06501482"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer","colon-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06501482","phase":"3","setting":"\"Interest of Postoperative Reintroduction of Chemotherapy in Patients Undergoing Resection of Colorectal Liver Metastases After Good Response to FOLFIRI-based Chemotherapy With or Without Targeted Agent\" (Intergroup FRENCH- PRODIGE)","sponsor":"Assistance Publique - Hôpitaux de Paris","enrolled":254,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06501482/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"},{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}