{"entity":{"id":"nct06518057","kind":"trial","name":"Hippocampal-avoidance craniospinal irradiation","aka":["Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer"],"tldr":"This study tests radiation to the brain and spinal cord while reducing radiation to a brain region involved in memory. It examines cancer control and effects on brain function.","summary":"This study tests radiation to the brain and spinal cord while reducing radiation to a brain region involved in memory. It examines cancer control and effects on brain function.\n\nInterventional study registered as NCT06518057, sponsored by University of Washington. Registry phase: 2. Registry enrollment is 22 participants (estimated). Registry status checked October 10, 2026: recruiting. UCSF lists this study as closed to local enrollment; local availability and overall registry status are separate. See the registry for full eligibility and current sites.","status":"recruiting","asOf":"2026-10-10","links":[{"label":"ClinicalTrials.gov NCT06518057","url":"https://clinicaltrials.gov/study/NCT06518057"},{"label":"UCSF study listing and local availability","url":"https://clinicaltrials.ucsf.edu/trial/NCT06518057"}],"tags":["ucsf-breast-coverage","interventional"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["ucsf"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06518057","phase":"2","setting":"Leptomeningeal metastases from breast cancer or non-small cell lung cancer","sponsor":"University of Washington","participation":[{"nct":"NCT06518057","source":"https://clinicaltrials.gov/study/NCT06518057","fetchedAt":"2026-10-10T20:54:21.385616Z","studySha256":"12b17bb6624d6731462ebb7a3e9ec1bee6801c492fff7f6b30d54b2cd35f04d9","overallStatus":"RECRUITING","lastUpdatePosted":"2026-08-14","leadSponsor":"University of Washington","collaboratorCount":0,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":22,"enrolmentType":"ESTIMATED","siteCount":3,"recruitingSiteCount":2,"countries":["United States"]}],"started":"2025-03-03","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06518057/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"institution":[{"id":"ucsf","kind":"institution","name":"UCSF Helen Diller Family Comprehensive Cancer Center","route":"/institutions/ucsf/"}]}}