{"entity":{"id":"nct06551116","kind":"trial","name":"QuantifyHER","aka":["QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer"],"tldr":"QuantifyHER evaluates more precise ways to measure HER2 in tumors. It asks whether these measurements help distinguish people who respond to trastuzumab deruxtecan from those who do not.","summary":"QuantifyHER evaluates more precise ways to measure HER2 in tumors. It asks whether these measurements help distinguish people who respond to trastuzumab deruxtecan from those who do not.\n\nObservational study registered as NCT06551116, sponsored by Abramson Cancer Center at Penn Medicine. Registry enrollment is 200 participants (estimated). Registry status checked October 10, 2026: recruiting. UCSF lists this study as open to eligible people; local availability and overall registry status are separate. See the registry for full eligibility and current sites.","status":"recruiting","asOf":"2026-10-10","links":[{"label":"ClinicalTrials.gov NCT06551116","url":"https://clinicaltrials.gov/study/NCT06551116"},{"label":"UCSF study listing and local availability","url":"https://clinicaltrials.ucsf.edu/trial/NCT06551116"}],"tags":["ucsf-breast-coverage","observational"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["ucsf"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06551116","phase":"observational","setting":"HER2-low metastatic breast cancer receiving trastuzumab deruxtecan","sponsor":"Abramson Cancer Center at Penn Medicine","participation":[{"nct":"NCT06551116","source":"https://clinicaltrials.gov/study/NCT06551116","fetchedAt":"2026-10-10T20:54:19.475932Z","studySha256":"29bdcd90712e9c920da05c3a6c2f6a9976d97a6b39b70f383c41eac68e8da5ad","overallStatus":"RECRUITING","lastUpdatePosted":"2026-07-08","leadSponsor":"Abramson Cancer Center at Penn Medicine","collaboratorCount":2,"minimumAge":"18 Years","sex":"ALL","healthyVolunteers":false,"hasEligibility":true,"enrolment":200,"enrolmentType":"ESTIMATED","siteCount":37,"recruitingSiteCount":37,"countries":["United States"]}],"started":"2024-10-10","startedType":"actual","enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06551116/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"institution":[{"id":"ucsf","kind":"institution","name":"UCSF Helen Diller Family Comprehensive Cancer Center","route":"/institutions/ucsf/"}]}}