{"entity":{"id":"nct06580002","kind":"trial","name":"Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial","aka":[],"tldr":"A phase 2 trial in pancreatic cancer, run by University of California, Irvine, now recruiting.","summary":"Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial is a phase 2, randomised interventional study registered as NCT06580002 by University of California, Irvine, with a registry enrolment figure of 75 participants, started 2024-12-02 and due to reach its primary completion in 2027-07. Interventions recorded: Riluzole; Placebo. Conditions listed: Breast Cancer; Sarcoma; Gastric Cancer; Lung Cancer; Head and Neck Cancer; Colorectal Cancer; Ovarian Cancer; Liver Cancer; Genitourinary Cancer; Gynecologic Cancer; Urinary Bladder Cancer; Leukemia; Lymphoid Leukemia; Myeloma Multiple; Prostate Cancer; Pancreas Cancer; Non-hodgkin Lymphoma; Hodgkin Lymphoma; Brain Cancer; Melanoma; Mycosis Fungoides; Kidney Cancer. Primary outcome: Change in circulating Brain-Derived Neurotrophic Factor (BDNF) levels over time in cancer survivors experiencing cognitive impairment (CRCI). Sites: United States. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06580002","url":"https://clinicaltrials.gov/study/NCT06580002"}],"tags":["ctgov-ingest","pancreatic-deep-dive"],"related":[],"cancers":["pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06580002","phase":"2","setting":"Repurposing Riluzole for Augmenting Brain-Derived Neuropathic Factor (BDNF) Levels and Cognitive Function in Patients Experiencing Cancer-Related Cognitive Impairment: An Interventional Pilot Clinical Trial","sponsor":"University of California, Irvine","enrolled":75,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06580002/","neighbours":{"cancer":[{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"term":[{"id":"pancreatic-trials-open-today","kind":"term","name":"Pancreatic cancer trials open today (registry snapshot and UK sites)","route":"/terms/pancreatic-trials-open-today/"}]}}