{"entity":{"id":"nct06586957","kind":"trial","name":"A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors","aka":[],"tldr":"A phase 1 trial of NKT3964 run by NiKang Therapeutics, Inc., now recruiting.","summary":"A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors is a phase 1 interventional study registered as NCT06586957 by NiKang Therapeutics, Inc., with 238 participants planned, started 2024-09-19, primary completion expected 2029-01. Conditions recorded: Solid Tumor, Advanced Solid Tumor, Solid Tumor, Adult, Metastatic Tumor, Ovarian Cancer, Ovarian Neoplasms, Ovarian Carcinoma, Metastatic Ovarian Carcinoma, Endometrial Neoplasms, Endometrial Diseases, Metastatic Endometrial Cancer, Triple Negative Breast Cancer, Metastatic Endometrial Carcinoma, Advanced Endometrial Carcinoma, Advanced Ovarian Carcinoma, Gastric Cancer, Advanced Gastric Carcinoma, Metastatic Gastric Cancer, Metastatic Gastric Carcinoma, Small Cell Lung Cancer, Small Cell Lung Carcinoma, Triple Negative Breast Neoplasms, Platinum-resistant Ovarian Cancer, Platinum-refractory Ovarian Carcinoma, CCNE1 Amplification, Hormone Receptor Negative Breast Carcinoma, Human Epidermal Growth Factor 2 Negative Carcinoma of Breast, Progesterone-receptor-positive Breast Cancer. Interventions recorded: NKT3964, Paclitaxel, Doxorubicin.","status":"recruiting","asOf":"2026-11-04","links":[{"label":"ClinicalTrials.gov NCT06586957","url":"https://clinicaltrials.gov/study/NCT06586957"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["endometrial","ovarian"],"sections":[],"technologies":[],"targets":[],"drugs":["nkt3964"],"companies":["nikang-therapeutics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06586957","phase":"1","setting":"A Phase 1, First-in-human, Open-label Study to Evaluate the Safety, Tolerability, PK, and Preliminary Anti-tumor Activity of the Novel Oral CDK2 Degrader NKT3964 in Adults With Advanced/Metastatic Solid Tumors","sponsor":"NiKang Therapeutics, Inc.","enrolled":238,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06586957/","neighbours":{"cancer":[{"id":"endometrial","kind":"cancer","name":"Endometrial cancer","route":"/cancers/endometrial/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"}],"drug":[{"id":"nkt3964","kind":"drug","name":"NKT3964","route":"/drugs/nkt3964/"}],"company":[{"id":"nikang-therapeutics","kind":"company","name":"NiKang Therapeutics","route":"/companies/nikang-therapeutics/"}]}}