{"entity":{"id":"nct06594692","kind":"trial","name":"Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study","aka":["mRCAT-C"],"tldr":"A phase 2 trial in colorectal cancer, run by Sir Run Run Shaw Hospital, not yet recruiting.","summary":"Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study is a phase 2, randomised interventional study registered as NCT06594692 by Sir Run Run Shaw Hospital, with a registry enrolment figure of 140 participants, started 2024-10 and due to reach its primary completion in 2025-09-30. Interventions recorded: Node-Sparing Short-Course Radiotherapy Combined with CAPOX and Sintilimab; CAPOX Chemotherapy. Conditions listed: Microsatellite Stable (MSS) Colon Cancer; Locally Advanced Colon Cancer. Primary outcome: pathological complete response rate. Colorectal eligibility wording from the registry: \"Tumor confirmed by colonoscopy and enhanced abdominal CT to be ≥ 12 cm from the anal verge\". Sites: China. No results are recorded here; the registry entry is the source.","status":"planned","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06594692","url":"https://clinicaltrials.gov/study/NCT06594692"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06594692","phase":"2","setting":"Node-sparing Modified Short-Course Radiation Combined With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer : A Randomized, Prospective, Multicenter, Open-label Clinical Trial","sponsor":"Sir Run Run Shaw Hospital","enrolled":140,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06594692/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}