{"entity":{"id":"nct06598007","kind":"trial","name":"A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors","aka":[],"tldr":"A phase 1/2 trial of FOLFOX, FLOT, CAPOX in colorectal cancer and pancreatic ductal adenocarcinoma, run by Crossignal Therapeutics, Inc., now recruiting.","summary":"A Study to Determine the Effect of CT3001 in Patients With Advanced Solid Tumors is a phase 1/2 interventional study registered as NCT06598007 by Crossignal Therapeutics, Inc., with 78 participants planned, started 2024-09-20 and due to reach its primary completion in 2027-06-20. Interventions recorded: CT3001, FOLFOX (5-fluorouracil, Leucovorin, Oxaliplatin). Conditions listed: Solid Tumor, Adult, Colorectal Cancer, Pancreatic Ductal Adenocarcinoma. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06598007","url":"https://clinicaltrials.gov/study/NCT06598007"}],"tags":["ctgov-ingest"],"related":[],"cancers":["colorectal","pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":["folfox","flot","capox"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"notes":[],"nct":"NCT06598007","phase":"1/2","setting":"A Phase 1/2 First-In-Human, Open-Label, Multicenter, Dose Escalation and Dose Expansion Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CT3001 in Patients With Advanced Solid Tumors","sponsor":"Crossignal Therapeutics, Inc.","enrolled":78,"outcomes":[]},"route":"/trials/nct06598007/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"drug":[{"id":"capox","kind":"drug","name":"CAPOX (capecitabine, oxaliplatin)","route":"/drugs/capox/"},{"id":"ct3001","kind":"drug","name":"CT3001","route":"/drugs/ct3001/"},{"id":"flot","kind":"drug","name":"FLOT (5-FU, leucovorin, oxaliplatin, docetaxel)","route":"/drugs/flot/"},{"id":"folfox","kind":"drug","name":"FOLFOX (5-FU, leucovorin, oxaliplatin)","route":"/drugs/folfox/"}]}}