{"entity":{"id":"nct06607796","kind":"trial","name":"Efficacy and Safety of Intratumoral Toluenesulfonamide (PTS) Injection in Stage IV Driver Gene-Negative NSCLC With/Without Chemoimmunotherapy","aka":[],"tldr":"A phase 3 trial in lung cancer, run by Zhou Chengzhi, now recruiting.","summary":"Efficacy and Safety of Intratumoral Toluenesulfonamide (PTS) Injection in Stage IV Driver Gene-Negative NSCLC With/Without Chemoimmunotherapy is a phase 3, randomised interventional study registered as NCT06607796 by Zhou Chengzhi, with a registry enrolment figure of 180 participants, started 2024-03-01 and due to reach its primary completion in 2026-12. Interventions recorded: Toluenesulfonamide (PTS) Intratumoral Injection. Conditions listed: Lung Cancer. Primary outcome: Objective response rate(ORR). Lung eligibility wording from the registry: \"Histologically or cytologically confirmed stage IV (AJCC 8th edition) driver gene negative non-small cell lung cancer；\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-25","links":[{"label":"ClinicalTrials.gov NCT06607796","url":"https://clinicaltrials.gov/study/NCT06607796"}],"tags":["ctgov-ingest","lung-deep-dive"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06607796","phase":"3","setting":"A Multicenter Study of the Efficacy and Safety of Intratumoral Injection of Toluenesulfonamide (PTS) in Combination With or Without First-line Chemoimmunotherapy Based on Standard Treatment for Stage IV Driver Gene-negative Non-small Cell Lung Cancer","sponsor":"Zhou Chengzhi","enrolled":180,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06607796/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"term":[{"id":"lung-trials-open-today","kind":"term","name":"Lung cancer trials open today (registry snapshot)","route":"/terms/lung-trials-open-today/"}]}}