{"entity":{"id":"nct06617169","kind":"trial","name":"Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors","aka":[],"tldr":"A phase 1 trial of MNPR-101 run by Monopar Therapeutics, active and no longer recruiting.","summary":"Dose-Escalation of MNPR-101-PCTA-177Lu in Solid Tumors is a phase 1 interventional study registered as NCT06617169 by Monopar Therapeutics, with 12 participants planned, started 2024-10-08. Conditions recorded: Solid Tumor, Adult, Bladder Cancer, Urothelial Carcinoma, Triple-negative Breast Cancer, Lung Cancer, Colorectal Cancer, Gastric Cancer, Ovarian Cancer and Pancreatic Cancer. Interventions recorded: MNPR-101-PCTA-177Lu.","status":"active","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT06617169","url":"https://clinicaltrials.gov/study/NCT06617169"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","urothelial","tnbc","lung-cancer","colorectal","gastric","ovarian","pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":["mnpr-101"],"companies":["monopar"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06617169","phase":"1","setting":"Open Label, Phase 1a, Dose-Escalation Study Evaluating the Safety of Fractionated MNPR-101-PCTA-177Lu Dosing in the Treatment of Solid Tumor Cancers","sponsor":"Monopar Therapeutics","enrolled":12,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06617169/","neighbours":{"cancer":[{"id":"urothelial","kind":"cancer","name":"Bladder & urothelial cancer","route":"/cancers/urothelial/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"},{"id":"lung-cancer","kind":"cancer","name":"Lung cancer (all types)","route":"/cancers/lung-cancer/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"drug":[{"id":"mnpr-101","kind":"drug","name":"MNPR-101","route":"/drugs/mnpr-101/"}],"company":[{"id":"monopar","kind":"company","name":"Monopar Therapeutics","route":"/companies/monopar/"}]}}