{"entity":{"id":"nct06630624","kind":"trial","name":"Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM","aka":["INJECTABL-II"],"tldr":"A phase 1/2 trial in colorectal cancer, run by M.R. Meijerink, now recruiting.","summary":"Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM is a phase 1/2, interventional study registered as NCT06630624 by M.R. Meijerink, with a registry enrolment figure of 120 participants, started 2024-07-10 and due to reach its primary completion in 2029-08-01. Interventions recorded: IP-001. Conditions listed: Colorectal Cancer; Liver Metastases; Liver Metastasis Colon Cancer. Primary outcome: Maximum Tolerated Dose (MTD) (Phase 1); 1-Year Distant Progression Free Survival (DPFS) (Phase 2 part 1); Disease Control Rate (DCR) (Phase 2 part 2). Sites: Netherlands. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06630624","url":"https://clinicaltrials.gov/study/NCT06630624"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["colon-cancer"],"sections":[],"technologies":["thermal-ablation"],"targets":[],"drugs":[],"companies":["angiodynamics"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06630624","phase":"1/2","setting":"INJECTABL-II: Dose Finding, Efficacy and Immunological Response of a Novel Immuno-Adjuvant (IP-001) Following Microwave Ablation or Irreversible Electroporation for Colorectal Liver Metastases.","sponsor":"M.R. Meijerink","enrolled":120,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06630624/","neighbours":{"cancer":[{"id":"colon-cancer","kind":"cancer","name":"Colon cancer (adenocarcinoma of the colon)","route":"/cancers/colon-cancer/"}],"technology":[{"id":"thermal-ablation","kind":"technology","name":"Thermal ablation (RFA, microwave, cryo)","route":"/technologies/thermal-ablation/"}],"company":[{"id":"angiodynamics","kind":"company","name":"AngioDynamics","route":"/companies/angiodynamics/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}