{"entity":{"id":"nct06636435","kind":"trial","name":"A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer","aka":[],"tldr":"A phase 1 trial of CBA-1205 run by Chiome Bioscience Inc., now recruiting.","summary":"A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer is a phase 1 interventional study registered as NCT06636435 by Chiome Bioscience Inc., with 66 participants planned, started 2020-06-01. Conditions recorded: Solid Tumors, Hepatocellular Carcinoma (HCC), Malignant Melanoma and Pediatric Cancer. Interventions recorded: CBA-1205 Part 1, CBA-1205 Part 2, CBA-1205 Part 3, CBA-1205 Part 4 and CBA-1205 Part 5.","status":"recruiting","asOf":"2026-11-03","links":[{"label":"ClinicalTrials.gov NCT06636435","url":"https://clinicaltrials.gov/study/NCT06636435"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["metastatic-cancer","hcc","childhood-cancers","melanoma"],"sections":[],"technologies":[],"targets":[],"drugs":["cba-1205"],"companies":["chiome-bioscience"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06636435","phase":"1","setting":"A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors.","sponsor":"Chiome Bioscience Inc.","enrolled":66,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06636435/","neighbours":{"cancer":[{"id":"childhood-cancers","kind":"cancer","name":"Childhood cancers (all types)","route":"/cancers/childhood-cancers/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"},{"id":"metastatic-cancer","kind":"cancer","name":"Metastatic cancer (cancer that has spread)","route":"/cancers/metastatic-cancer/"}],"drug":[{"id":"cba-1205","kind":"drug","name":"CBA-1205","route":"/drugs/cba-1205/"}],"company":[{"id":"chiome-bioscience","kind":"company","name":"Chiome Bioscience","route":"/companies/chiome-bioscience/"}]}}