{"entity":{"id":"nct06647680","kind":"trial","name":"Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01）","aka":[],"tldr":"A phase 2 trial of capecitabine in colorectal cancer, run by The Affiliated Hospital of Qingdao University, now recruiting.","summary":"Neoadjuvant Chemotherapy and PD-1 Inhibitor for Locally Advanced Rectal Cancer（CONTROL-01） is a phase 2, interventional study registered as NCT06647680 by The Affiliated Hospital of Qingdao University, with a registry enrolment figure of 35 participants, started 2025-06-01 and due to reach its primary completion in 2026-12-01. Interventions recorded: Receive the experimental combination of drugs (chemoradiation (Oxaliplatin and Capecitabine) + PD-1 inhibitor (Tislelizumab) for 3 cycles. Conditions listed: Rectal Cancer Patients. Primary outcome: Clinical complete response and pathological complete response. Colorectal eligibility wording from the registry: \"* Pathologically proven diagnosis of adenocarcinoma of the rectum\". Sites: China. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT06647680","url":"https://clinicaltrials.gov/study/NCT06647680"}],"tags":["ctgov-ingest","colorectal-deep-dive"],"related":[],"cancers":["rectal-cancer"],"sections":[],"technologies":["cytotoxic-chemotherapy","imrt-igrt"],"targets":[],"drugs":["capecitabine"],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06647680","phase":"2","setting":"Neoadjuvant Chemotherapy and Tislelizumab (PD-1 Inhibitior) for Locally Advanced Rectal Cancer: a Single-center, Prospective, Phase II Study","sponsor":"The Affiliated Hospital of Qingdao University","enrolled":35,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06647680/","neighbours":{"cancer":[{"id":"rectal-cancer","kind":"cancer","name":"Rectal cancer","route":"/cancers/rectal-cancer/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"},{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"drug":[{"id":"capecitabine","kind":"drug","name":"Capecitabine","route":"/drugs/capecitabine/"}],"term":[{"id":"colorectal-trials-open-today","kind":"term","name":"Colorectal cancer trials open today (registry snapshot)","route":"/terms/colorectal-trials-open-today/"}]}}